In Cape Town, South Africa, scientists have developed a genetically engineered maize variety resistant to the maize streak virus. This new maize appears to be the first GM crop developed and tested solely by Africans.
The research team around Dionne Shepherd used a gene that the pathogen requires to replicate itself and mutated it to make it non-functional. This gene was inserted into the plant to produce a mutated replication protein. When the attacking virus enters the plant cell, this mutated protein then recognises the native replication protein of the pathogen and, by binding to it, inhibits replication and renders the virus ineffective.
Field trials are expected soon and are aimed at testing the effectiveness of the technology as well as at ensuring that it has no unintended effects on beneficial organisms. The resistant maize also will be tested to confirm that the viral protein is safe and non-allergenic. It is estimated that the it will take approximately five years to prepare the GM maize for use as a commercial product. The scientist Dionne Shepherd admitted, however, that costs of the crop could be an issue for poor farmers.
Maize can supply 50 percent of the caloric intake in sub-Saharan Africa but, in certain years, entire crops may be destroyed by viral infection. For more than a quarter-century, scientists have been working on the development of maize varieties with differing degrees of resistance for the streak virus. |