Maize 59122 x 1507 x NK603
 Summary of risk assessment
| Opinion of the scientific panel on genetically modified organisms (GMO Panel) of the European Food Safety Authority (EFSA). | | Adopted |
03/04/2009 | | Conclusion | 59122x1507xNK603 maize is as safe as
its non genetically modified counterpart, and releasing 59122x1507xNK603 for processing and food and feed use is unlikely to cause adverse effects on human health and the environment. |
| Comparative analysis | | Basis of comparsion | Conventional maize cultivars
( isogenic line). | | Qualities of the plant | Several parameters were compared such as
agronomic performance and phenotypic characteristics. | | Compositional analysis | The following were investigated:
amongst others fatty acids, proteins, carbohydrates, amino acids, minerals, vitamins, fibre,
also characteristics like moisture and undesired substances such as trypsin inhibitors.
59122x1507xNK603 maize is compositionally equivalent to its non GM counterpart
and conventional maize except for the present of the new proteins. |
| Safety of food and feed | |
New protein (Cry34Ab1, Cry35Ab1, Cry1F, PAT, CP4 EPSPS, CP4 EPSPS L214P) | No correspondence with known toxins. | | Allergenicity of the new protein | The
proteins present in the maize 59122x1507xNK603 have been assessed previously and
it was found unlikely that they are allergenic. Based on the information
provided, the GMO Panel considers it unlikely that potential interactions occur
that might change the allergenicity of the newly expressed proteins. | | Assessment for food and feed | As the
composition of maize 59122x1507xNK603 is comparable with that of non-GM maize
varieties and the single events and also no indication for interaction between
the newly expressed proteins was found, the GMO Panel is of the opinion that no
additional animal safety studies are required. | | Nutritional equivalence | The
feeding study supported the results of the comparative compositional analysis
that showed that 59122x1507xNK603 maize is compositionally and nutritionally
equivalent to non-GM maize comparators. |
| Enviromental safety | | Survivebility | Maize is highly domesticated and is not viable outside of cultivation. | | Out-crossing | Maize has no cross-compatible wild relatives in Europe. Out-crossing is only possible with maize in neighbouring fields. | | Field trials | Evaluation of field trails in the USA (2003),
Spain, Bulgaria and Hungary (2004). |
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