Maize 59122 x NK603
 Summary of risk assessment
| Opinion of the scientific panel on genetically modified organisms (GMO Panel) of the European Food Safety Authority (EFSA). |
| Adopted |
19/11/2008 |
| Conclusion |
59122xNK603 maize is as safe as conventional maize, and releasing
59122xNK603 for processing and food and feed use is unlikely to cause adverse effects on human health and the environment. |
| Comparative analysis |
| Basis of comparsion |
Conventional maize cultivars
( isogenic line). |
| Qualities of the plant |
Several parameters were compared such as field
germinatoin and external features. |
| Compositional analysis |
The following were investigated: the proportion and composition of fatty acids, proteins, carbohydrates, amino acids, minerals, vitamins, fibre,
also characteristics like moisture and undesired substances such as trypsin inhibitors.
No biologically significant changes were observed. |
| Safety of food and feed |
|
New protein (Cry34Ab1, Cry35Ab1, PAT, CP4 EPSPS, CP4 EPSPS L214P) |
No correspondence with known toxins. |
| Allergenicity of the new protein |
The
proteins present in the maize 59122 x NK603 have been assessed previously and it
was found unlikely that they are allergenic. It is unlikely that potential
interactions occur that might change the allergenicity of the expressed proteins. |
| Assessment for food and feed |
The
42-day feeding study was conducted on poultry fed transgenic maize
59122x1507xNK603. Animal performance on various diets were evaluated by
measuring mortality, weight gain, organ and carcass yields, and feed efficiency.
and were compared with control groups that were fed conventional maize.
No biologically significant differences were observed. |
| Nutritional equivalence |
The
feeding study supported the results of the comparative compositional analysis
that showed that 59122xNK603 maize is compositionally and nutritionally
equivalent to non-GM maize comparators. |
| Enviromental safety |
| Survivebility |
Maize is highly domesticated and is not viable outside of cultivation. |
| Out-crossing |
Maize has no cross-compatible wild relatives in Europe. Out-crossing is only possible with maize in neighbouring fields. |
| Field trials |
Evaluation of field trails in the USA (2003), Europe (2004). |
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