May 22, 2012 | 3:43 pm

Mais Bt176

 Summary of risk assessment
 

Opinion of the former Scientific Committee on Plants (SCF)
Adopted 21/02/1997
Conclusion Bt176 maize is as safe as conventional maize, and releasing Bt176 for food and feed use is unlikely to cause adverse effects on human health and the environment.

 

Comparative analysis
Basis of comparison Conventional counterpart (isogenic line).

 

Safety of food and feed
New proteins
(CRY1A(b)+PAT)		 Feeding studies on mice: test animals did not show signs of acute toxicity.

Comparison with known toxins: No correspondence.

Allergenicity of the new protein(s) No correspondence with known allergens (amino acid sequence comparison).

The protein(s) are rapidly broken down during digestion.

Digestive juices containig pepsin break down and deactivate the PAT protein.

Horizontal gene transfer Studies have shown that large, functional fragments of DNA are not taken up by microorganisms.
Nutritional equivalence No significant changes in nutritional value were found between the GM maize and its conventional counterpart.

 

Environmental safety
Surviveability Maize is highly domesticated and is not viable outside of cultivation.
Out-crossing Maize has no cross-compatible wild relatives in Europe. Out-crossingis only possible with maize in neighbouring fields.