GMO COMPASS - Information on genetically modified organisms
  Mar 27, 2017 | 8:14 pm
Site Search

Searches all of GMO-Compass in an instant




Stakeholder input wanted: survey on research needs for assessing GMO impacts 

Shaping the Future of GMO Research

Stakeholder with interests in the risk and/or benefit assessment of Genetically Modified Organisms (GMO’s) are invited to take part in an online survey.

The aim of this survey is to identify which research needs should be prioritised, thereby contributing to the commissioning of research on the health, environment and economic impacts of GMOs.

The survey will close on 15th July 2015.

More information and access to the online survey

The setting-up of this website was financially supported by the European Union within the European Commission’s Sixth Framework Programme from 1 January 2005 until 28 February 2007.

The European Commission and other EU agencies are not responsible for the content.
See what’s what.
The GMO Food Database
The GMO Food Database.
You want to know for which food products or plants gene technology plays a role?

Then enter here the name of a plant, foodstuff, ingredient or additive:

Database search
All database entries in overview:
Plants
Foodstuffs
Ingredients and additives
Additives according to E numbers
Enzymes


Please note that the GMO Compass Database currently is being expanded and updated. Please check back for new entries.

Newsletter
Sign up to receive regular updates on GM food quality and safety.
To change or cancel your subscription, please enter your email above.
Contact
Comments, suggestions or questions?
Please contact us at info@gmo-compass.org
Change font size
1 2 3

Vitamin B12

 

Possible application of gene technology Labelling
Producible with help of GM microorganisms no

 

Description

Vitamin B12 (also known as cobalamine) is necessary for the growth and division of cells, particularly in the case of red blood corpuscles. This vitamin is not produced in the human body and consequently must be obtained from nutrition. It occurs primarily in food products derived from animal sources, such as liver, kidneys, meat, milk and eggs. It also is found in beer.

Generally, the comparatively low amounts of B12 required are supplied by a normal diet. However, as many as 30 per cent of individuals older than 60 years may suffer from a deficit of B12. This is due to the age-related bodily decline in the ability to produce the compound known as the "intrinsic factor" that makes the vitamin metabolically accessible. A deficit of B12 may damage the nervous system and, for example, may lead to a sensation of numbness in the hands and feet, as well as to a decrease in cognitive performance. Strict vegetarians also may suffer from a deficit of vitamin B12.

Application

As a vitamin supplement, e.g.:

Gene technology

Manufacture: the chemical synthesis of vitamin B12 is extremely difficult and labour-intensive. For this reason, bio-technical processes are largely dominant in its production. It may be assumed in the meanwhile that vitamin B12 is manufactured as a rule with the aid of genetically modified microorganisms.

Approval: ingredients or additives that are produced with the aid of GM microorganisms are assumed not to be addressed by the EU decree 1829/2003 (GM food and feed). Hence, special approval does not exist for vitamin B12 that is produced in this manner.

Labelling: additives produced in closed systems with the aid of GM micro-organisms are not subject to a labelling requirement, provided that the additive in question has been purified and does not contain microorganisms.

The additive in question remains exempt from labelling even in the case that the microorganisms used in its production have obtained nutrients derived from GM plants.

Vitamin B12 preparations with intrinsic factor: the Cobento A/S company has developed a nutritional supplement that contains vitamin B12 and "intrinsic factor".

The intrinsic factor is a protein that is formed in the digestive tract and that binds B12, thereby protecting the vitamin from being broken down by digestive enzymes. Vitamin B12 is then absorbed by specific receptors in the small intestine. Due to reasons of genetic inheritance or age, it may occur that this protein is formed in insufficient quantities or not at all, which leads to a deficiency of vitamin B12.

Thale cress (Arabidopsis thaliana) is used in the harvest of intrinsic factor. The plant was genetically modified to produce the protein in its leaves. The derived preparation is intended to prevent a deficiency of vitamin B12. An application for its approval has been submitted to the European Food Safety Authority (EFSA).

 

November 26, 2008 [nach oben springen]

© 2017 by GMO Compass. All rights reserved. | Imprint | website created by webmotive